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FGFR4 (DMC460) IgG1 Chimeric mAb

Anti-FGFR4 (DMC460) IgG1 Chimeric Monoclonal Antibody
5/5

$445.00

Cat.#:  28236

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28236
Product Name:   Anti-FGFR4(DMC460) IgG1 Chimeric Monoclonal Antibody
Synonyms:   CD334; JTK2; TKF
Description:    Anti-FGFR4 antibody(DMC460) IgG1 Chimeric Monoclonal Antibody
Background:    The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways; including cell proliferation; cell differentiation; cell migration; lipid metabolism; bile acid biosynthesis; vitamin D metabolism; glucose uptake; and phosphate homeostasis. This protein consists of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment; and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. [provided by RefSeq; Aug 2017]
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human FGFR4
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-FGFR4 (DMC460) on Expi293 cells transfected with human FGFR4 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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