Subtotal:
$347.00
$4,400.00
| Cat.#: 11120 | ||
| Product Name: Human FZD4 Full Length Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: CD344; EVR1; FEVR; Fz-4; Fz4; FZD4S; FzE4; GPCR; hFz4 | ||
| Target: FZD4 | ||
| UNIPROT ID: Q9ULV1 | ||
| Description: Human FZD4 full length protein-synthetic nanodisc | ||
| Background: A member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The human full length FZD4 protein has a MW of 60.3 kDa | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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