$239.00
Gα12 Monoclonal Antibody
| Cat. #: 26026 |
| Gene Symbol: GNA12 |
| Description: Anti-Gα12 Mouse Monoclonal Antibody |
| Background: Heterotrimeric G proteins are essential cellular signal transducers. Gα12 is a member of the G12/13 subfamily of G proteins. Biochemical and physiological functions of Gα12 are being explored. |
| Immunogen: A synthetic peptide from the N-terminal region of human Gα12 protein |
| Applications: ELISA, WB, IHC, IP |
| Recommended Dilutions: ELISA 1:1000-1:5000 WB 1:100-1:2000 IHC 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Gαq subfamily antibody recognizes all members of the Gq subfamily of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
| Western blot: Western blot analysis of Gα12 proteins. MEF whole-cell lysate was used for western blot with anti- Gα12 mouse monoclonal antibody (cat. # 26026). |
| 1. Conformational Profiling of the AT1 Angiotensin II Receptor Reflects Biased Agonism, G Protein Coupling, and Cellular ContextJ Biol Chem. 2017 PMID: 28213525 |
| 2. Gα12 gep oncogene deregulation of p53-responsive microRNAs promotes epithelial-mesenchymal transition of hepatocellular carcinomaOncogene. 2014 PMID: 25065598 |
