$239.00
Gα13 Monoclonal Antibody
| Cat. #: 26004 |
| Gene Symbol: Gna13 |
| Description: Anti-Gα13 Mouse Monoclonal Antibody |
| Background: Heterotrimeric G proteins are essential cellular signal transducers. Gα13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Gα13 are being explored. |
| Immunogen: Recombinant full length Gα13 protein |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA 1:1000-1:5000, WB 1:1000-1:2000 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Gα13 monoclonal antibody recognizes Gα13 of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: Gα13, Gα12 or Gαq plasmid DNAs were transiently transfected into CHO cells (endogenous Gα13 protein was down-regulated by Gα13siRNA). Whole-cell lysates were used for western blots. |
| 1. PLEXIN-B2 promotes the osteogenic differentiation of human bone marrow mesenchymal stem cells via activation of the RhoA signaling pathway Cell Signal. 2019 PMID: 31176746 |
| 2. The interaction of Ga13 with integrin ß1 mediates cell migration by dynamic regulation of RhoA Mol Biol Cell. 2015 PMID: 26310447 |
| 3. B-lymphocyte Specific loss of Ric-8A Results in a Gα Protein Deficit and Severe Humoral Immunodeficiency J Immunol. 2015 PMID: 26232433 |
| 4. Evidence of a common mechanism of disassembly of adherens junctions through Ga13 targeting of VE-cadherin J Exp Med. 2014 PMID: 24590762 |
| 5. A directional switch of integrin signaling and a new anti-thrombotic strategy Nature. 2013 PMID: 24162846 |
| 6. Suppression of Tumor Angiogenesis by Ga13 Haploinsufficiency J Biol Chem. 2009 PMID: 19654325 |
