NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$239.00
Gαo Monoclonal Antibody
Cat. #: 26009 |
Gene Symbol: Gnao |
Description: Anti-Gαo Mouse Monoclonal Antibody |
Background: Heterotrimeric G proteins are critical cellular signal transducers. Gαobelongs to the Gi sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of Gαo proteins are being explored. |
Immunogen: Recombinant full length protein of Gαo |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA 1:1000-1:5000 WB 1:100-1:2000 |
Concentration: 1 mg/ml |
Host Species: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: IgG |
Purity: Purified from ascites |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Gαo antibody recognizes Gαo of vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: Whole-cell lysate of MEF cells was used for western blots with the monoclonal anti- Gαo antibody (Cat # 26009). |
2. Identification and Characterization of the Role of REEP5 in Sarco-Endoplasmic Reticulum Formation, Maintenance, and Function in Cardiac Muscle tspace.library.utoronto.ca. 2021 PMID: |
2. Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium Sci Data. 2020 PMID: 33262348 |
2. Social Isolation Induces Rac1-Dependent Forgetting of Social Memory Cell Rep. 2018 PMID: 30304669 |