NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$239.00
Gαs Monoclonal Antibody
Cat. #: 26006 |
Gene Symbol: Gnas |
Description: Anti-Gαs Mouse Monoclonal Antibody |
Background: Heterotrimeric G proteins are critical cellular signal transducers .Gαsrepresents one sub-family of G proteins that could mediate the stimulation of adenylyl cyclases. |
Immunogen: Recombinant full length protein of Gαs |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA 1:1000-1:5000,WB 1:1000-1:2000,IHC 1:100-1:200 |
Host Species: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: IgG |
Purity: Purified from ascites |
Preservative: No |
Constituents: PBS(without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol |
Species Reactivity: Gαs antibody recognizes Gαs of vertebrates |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot: Western blot analysis of Gαs proteins. MEF whole-cell lysate was used for western blots. |
1. Latrophilins are essential for endothelial junctional fluid shear stress mechanotransduction bioRxiv. 2020 PMID: |
2. Acupuncture upregulates G protein coupled activity in SAMP8 mice Acupunct Med. 2017 PMID: 28450287 |
3. Neuronal NF1/RAS regulation of cyclic AMP requires atypical PKC activation Hum Mol Genet. 2014 PMID: |