| Cat.#: 28349 |
| Product Name: Anti-GITR Ligand(DM52) Rabbit Monoclonal Antibody |
| Synonyms: TNFSF18; AITRL; TL6; hGITRL; GITR Ligand |
| Description: Anti-GITR Ligand antibody(DM52) Rabbit Monoclonal Antibody |
| Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18:AITR:GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells; and is thought to be important for interaction between T lymphocytes and endothelial cells. |
| Applications: ELISA; Flow Cyt |
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 |
| Host Species: Rabbit |
| Isotype: Rabbit IgG |
| Purification: Purified from cell culture supernatant by affinity chromatography |
| Species Reactivity: Human GITR Ligand |
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
 
Figure 1. Expi 293 cell line transfected with irrelevant protein (A) and human GITR-L (B) were surface stained with Rabbit anti-GITR-L monoclonal antibody 15µg/ml ( clone: DM52) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody. | 
Figure 2. Flow cytometry data of serially titrated Rabbit anti-GITR-L monoclonal antibody ( clone: DM52) on H929 cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used. |
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