| Cat.#: 11094 |
| Product Name: Human GLP2R Full Length Protein |
| Size : 10 µg; 50 µg and 100 µg |
| Synonyms: GLP-2-R; GLP-2R |
| Target: GLP2R |
| UNIPROT ID: O95838 |
| Description: Human GLP2R Full Length Protein-Synthetic Nanodisc |
| Background: A G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. |
| Species/Host: HEK293 |
| Molecular Weight: The human full length GLP2R protein has a MW of 63.0 kDa |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Protein Families: Druggable Genome, GPCR, Transmembrane |
| Protein Pathways: Neuroactive ligand-receptor interaction |
Figure 1. Elisa plates were pre-coated with Flag Tag GLP2R-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with GLP2R-Nanodisc is 2.975ng/ml. | 
Figure 2. Human GLP2R-Nanodisc, Flag Tag on SDS-PAGE |
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