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GP6 (DMC427) IgG1 Chimeric mAb

Anti-GP6 (DMC427) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28221

   Size:   100 μg

In Stock

            Product Description          
Cat.#:   28221
Product Name:   Anti-GP6(DMC427) IgG1 Chimeric Monoclonal Antibody
Synonyms:   BDPLT11; GPIV; GPVI
Description:    Anti-GP6 antibody(DMC427) IgG1 Chimeric Monoclonal Antibody
Background:    This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human GP6
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-GP6 (DMC427) on Expi293 cells transfected with human GP6 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).