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GPA33 (DMC497) IgG1 Chimeric mAb

Anti-GPA33 (DMC497) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28270

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28270
Product Name:   Anti-GPA33(DMC497) IgG1 Chimeric Monoclonal Antibody
Synonyms:   A33
Description:    Anti-GPA33 antibody(DMC497) IgG1 Chimeric Monoclonal Antibody
Background:    The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region; a single transmembrane domain; and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq; Jul 2008]
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human GPA33
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-GPA33 (DMC497) on Expi293 cells transfected with human GPA33 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).