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Human GPRC5D Full Length Protein

Human GPRC5D Full Length Protein-Synthetic Nanodisc


Cat.#:  11002

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11002
Product Name:   Human GPRC5D Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   GPRC5D
Target:    GPRC5D
Description:    Human GPRC5D full length protein-synthetic nanodisc
Background:     The protein encoded by this gene is a member of the G protein-coupled receptor family. Recent studies demonstrate that GPRC5D is expressed on malignant bone marrow plasma cells, whereas normal tissue expression is limited to the hair follicle. It may represent a potential target for effector-cell–mediated therapy to treat plasma-cell disorders like MM.
Species/Host:    HEK293
Molecular Weight:    The human full length GPRC5D Protein has a MW of 38.6 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were added with Flag Tag GPRC5D-Nanodisc (0.5 µg/per well) on an anti-Flag monoclonal antibody pre-coated (0.5 µg/per well) plate. Serial diluted anti-GPRC5D monoclonal antibody (28421) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-GPRC5D monoclonal antibody binding with GPRC5D-Nanodisc is 32.86ng/ml.

Figure2. Human GPRC5D-Nanodisc, Flag Tag on SDS-PAGE