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Human GRPR Full Length Protein

Human GRPR Full Length Protein-Synthetic Nanodisc
5/5

$4,400.00

Cat.#:  11099

   Size:   50 μg

3-4 weeks

            Product Description          
Cat.#:     11099
Product Name:   Human GRPR Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   BB2; BB2R; BRS2
Target:    GRPR
UNIPROT ID:    P30550
Description:    Human GRPR full length protein-synthetic nanodisc
Background:     Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
Species/Host:    HEK293
Molecular Weight:    The human full length GRPR protein has a MW of 43.2 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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