$445.00
Cat.#: 28205 |
Product Name: Anti-GUCY2C(DMC387) IgG1 Chimeric Monoclonal Antibody |
Synonyms: DIAR6; GC-C; GUC2C; MECIL; MUCIL; STAR |
Description: Anti-GUCY2C antibody(DMC387) IgG1 Chimeric Monoclonal Antibody |
Background: This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin; and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). |
Applications: Flow Cyt |
Recommended Dilutions: Flow Cyt 1:100 |
Host Species: Rabbit |
Isotype: Rabbit:Human Fc chimeric IgG1 |
Purification: Purified from cell culture supernatant by affinity chromatography |
Species Reactivity: Human GUCY2C |
Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
![]() Figure 1. Flow cytometry analysis with Anti-GUCY2C (DMC387) on Expi293 cells transfected with human GUCY2C (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |