Subtotal:
$445.00
$4,400.00
| Cat.#: 11114 | ||
| Product Name: Human HRH3 Full Length Protein | ||
| Size : 10 µg; 50 µg and 100 µg | ||
| Synonyms: GPCR97; HH3R | ||
| Target: HRH3 | ||
| UNIPROT ID: Q9Y5N1 | ||
| Description: Human HRH3 Full Length Protein-Synthetic Nanodisc | ||
| Background: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The human full length HRH3 protein has a MW of 48.7 kDa | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
| Protein Families: Druggable Genome, Transmembrane | ||
| Protein Pathways: Neuroactive ligand-receptor interaction | ||
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