Subtotal:
$347.00
$445.00
| Cat.#: 11138 | ||
| Product Name: Human 2B4 Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: CD244;2B4;SLAMF4;NKR2B4;NAIL;h2B4 | ||
| Target: 2B4 | ||
| UNIPROT ID: Q9BZW8 | ||
| Description: Recombinant human 2B4 protein with C-terminal mouse Fc and 6xHis tag | ||
| Background: This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The protein has a predicted molecular mass of 48.8 kDa after removal of the signal peptide. The apparent molecular mass of 2B4-mFc-His is approximately 70-100 kDa due to glycosylation. | ||
| Molecular Characterization: 2B4(Cys22-Ala221) mFc(Pro99-Lys330) 6×His | ||
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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