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Human CCR6 Protein, hFc Tag

Recombinant Human CCR6 with C-terminal human Fc tag
5/5

$415.00

Cat.#:  11456

   Size:   100 μg

In Stock

            Product Description          
Cat.#:     11456
Product Name:   Human CCR6 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   BN-1;C-C CKR-6;CC-CKR-6;CCR-6;CD196;CKR-L3;CKRL3;CMKBR6;DCR2;DRY6;GPR29;GPRCY4;STRL22
Target:    CCR6
UNIPROT ID:    P51684
Description:    Recombinant Human CCR6 with C-terminal human Fc tag
Background:     This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 31.6 kDa after removal of the signal peptide. The apparent molecular mass of CCR6-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    CCR6(Met1-Leu47) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CCR6 Protein, hFc Tag on SDS-PAGE under reducing condition.
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