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Human CD10 Protein, hFc Tag

Recombinant Human CD10 protein with N-terminal human Fc


Cat.#:  11312

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11312
Product Name:   Human CD10 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   MME;ALLA;D10;KFZp686O16152;GC126681;GC126707;EP;FE;eprilysin
Target:    CD10
UNIPROT ID:    P08473
Description:    Recombinant Human CD10 protein with N-terminal human Fc
Background:     The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 106.1 kDa after removal of the signal peptide.
Molecular Characterization:    hFc(Glu99-Ala330) CD10(Tyr52-Trp750)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CD10 Protein, hFc Tag on SDS-PAGE under reducing condition.