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Human CD1A Protein, hFc Tag

Recombinant human CD1A protein with C-terminal human Fc tag
5/5

$415.00

Cat.#:  11635

   Size:   100 μg

Under development

            Product Description          
Cat.#:     11635
Product Name:   Human CD1A Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD1;FCB6;HTA1;R4;T6
Target:    CD1A
UNIPROT ID:    P06126
Description:    Recombinant human CD1A protein with C-terminal human Fc tag
Background:     This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 56.76 kDa after removal of the signal peptide.
Molecular Characterization:    CD1A(Asn17-Val300) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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