Pioneering GTPase and Oncogene Product Development since 2010

Email us: info@neweastbio.com

Call us: 6109452007

Human CD20 Protein, hFc Tag

Recombinant Human CD20 protein with N-terminal human Fc
5/5

$445.00

Cat.#:  11172

   Size:   100 μg

In Stock

            Product Description          
Cat.#:     11172
Product Name:   Human CD20 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   B1;Bp35;CD20;CVID5;LEU-16;MS4A2;S7
Target:    CD20
UNIPROT ID:    P11836
Description:    Recombinant Human CD20 protein with N-terminal human Fc
Background:     This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 31.6 kDa after removal of the signal peptide.The apparent molecular mass of hFc-CD20 is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    hFc(Glu99-Ala330) CD20(Lys142-Ser188)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CD20 Protein, hFc Tag on SDS-PAGE under reducing condition.
          Publications