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Human CXCL1 Protein, hFc Tag

Recombinant Human CXCL1 with N-terminal human Fc tag


Cat.#:  11678

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11678
Product Name:   Human CXCL1 Protein
Size :    10 µg, 50 µg and 100 µg
Target:    CXCL1
UNIPROT ID:    P09341
Description:    Recombinant Human CXCL1 with N-terminal human Fc tag
Background:     This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 34.0 kDa after removal of the signal peptide.The apparent molecular mass of hFc-CXCL1 is approximately 35-40 kDa due to glycosylation.
Molecular Characterization:    hFc(Glu99-Ala330) CXCL1(Ala35-Asn107)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human CXCL1 Protein, hFc Tag on SDS-PAGE under reducing condition.