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Human DLK1 Protein, hFc Tag

Recombinant human DLK1 protein with C-terminal human Fc tag


Cat.#:  11739

   Size:   100 μg

Under development

          Product Description          
Cat.#:     11739
Product Name:   Human DLK1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Delta1;DLK;DLK-1;FA1;pG2;Pref-1;PREF1;ZOG
Target:    DLK1
UNIPROT ID:    P80370
Description:    Recombinant human DLK1 protein with C-terminal human Fc tag
Background:     This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 56.32 kDa after removal of the signal peptide.
Molecular Characterization:    DLK1 (Ala24-Gln303) hFc(Glu99-ALA330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.