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Human DSG2(50-609) Protein, His Tag

Recombinant Human DSG2(50-609) Protein with C-terminal 6XHis tag


Cat.#:  11943

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11943
Product Name:   Human DSG2(50-609) Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CDHF5;HDGC
Target:    DSG2
UNIPROT ID:    Q14126
Description:    Recombinant Human DSG2(50-609) Protein with C-terminal 6xHis tag
Background:     This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 63.3 kDa after removal of the signal peptide. The apparent molecular mass of DSG2(50-609)-His is approximately 70-100 kDa due to glycosylation.
Molecular Characterization:    DSG2(Ala50-Gly609) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human DSG2(50-609) Protein, His Tag on SDS-PAGE under reducing condition.