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Human EDA Protein, hFc Tag

Recombinant Human EDA Protein with N-terminal human Fc tag
5/5

$569.00

Cat.#:  11457

   Size:   100 μg

In Stock

            Product Description          
Cat.#:     11457
Product Name:   Human EDA Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   ED1;EDA2
Target:    EDA
UNIPROT ID:    Q92838
Description:    Recombinant Human EDA Protein with N-terminal human Fc tag
Background:     The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 50.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-EDA is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    hFc(Glu99-Ala330) EDA(Ser160-Ser391)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human EDA Protein, hFc Tag on SDS-PAGE under reducing condition.
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