Subtotal:
$347.00
$479.00
| Cat.#: 11218 | ||
| Product Name: Human EGFR Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: EGFR;RBB;RBB1;ER1;IG61;ENA | ||
| Target: EGFR | ||
| UNIPROT ID: P00533 | ||
| Description: Recombinant human EGFR Protein with C-terminal 6xHis tag | ||
| Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The protein has a predicted molecular mass of 69.4 kDa after removal of the signal peptide.The apparent molecular mass of EGFR-His is approximately 100-130 kDa due to glycosylation. | ||
| Molecular Characterization: EGFR(Leu25-Ser645) 6×His tag | ||
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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