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Human FASLG Protein, hFc Tag

Recombinant human FASLG with N-terminal human Fc tag


Cat.#:  11732

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11732
Product Name:   Human FASLG Protein
Size :    10 µg, 50 µg and 100 µg
Target:    FASLG
UNIPROT ID:    P48023
Description:    Recombinant human FASLG with N-terminal human Fc tag
Background:     This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 43.0 kDa after removal of the signal peptide. The apparent molecular mass of hFc-FASLG is approximately 35-55kDa due to glycosylation.
Molecular Characterization:    hFc(Glu99-Ala330) FASLG(Pro134-Leu281)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human FASLG Protein, N-hFc Tag on SDS-PAGE under reducing condition.