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Human GFAP (7-66) Protein, hFc Tag

Recombinant Human GFAP(7-66) with C-terminal human Fc tag


Cat.#:  11462

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11462
Product Name:   Human GFAP (7-66) Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   ALXDRD
Target:    GFAP
UNIPROT ID:    P14136
Description:    Recombinant Human GFAP(7-66) with C-terminal human Fc tag
Background:     This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 32.4 kDa after removal of the signal peptide. The apparent molecular mass of GFAP(7-66)-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    GFAP(Thr7-Arg66) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human GFAP(7-66) Protein, hFc Tag on SDS-PAGE under reducing condition.