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Human GM-CSFR Protein, hFc Tag

Recombinant Human GM-CSFR Protein with C-terminal human Fc tag


Cat.#:  11676

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11676
Product Name:   Human GM-CSFR Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   alphaGMR;CD116;CDw116;CSF2R;CSF2RAX;CSF2RAY;CSF2RX;CSF2RY;GM-CSF-R-alpha;GMCSFR;GMCSFR-alpha;GMR;GMR-alpha;SMDP4
Target:    GM-CSFR
UNIPROT ID:    P15509
Description:    Recombinant Human GM-CSFR Protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 60.6 kDa after removal of the signal peptide.The apparent molecular mass of GM-CSFR-hFc is approximately 70-130 kDa due to glycosylation.
Molecular Characterization:    GM-CSFR(Glu23-Gly320) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human GM-CSFR Protein, hFc Tag on SDS-PAGE under reducing condition.