Subtotal:
$347.00
$479.00
| Cat.#: 11252 | ||
| Product Name: Human GUCY2C Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: DIAR6;GC-C;GUC2C;MECIL;MUCIL;STAR | ||
| Target: GUCY2C | ||
| UNIPROT ID: P25092 | ||
| Description: Recombinant human GUCY2C protein with C-terminal 6xHis tag | ||
| Background: This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016] | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The protein has a predicted molecular mass of 46.8 kDa after removal of the signal peptide. The apparent molecular mass of GUCY2C-His is approximately 55-130 kDa due to glycosylation. | ||
| Molecular Characterization: GUCY2C(Ser24-Gln430) 6×His tag | ||
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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