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$525.00
| Cat.#: 11292 | ||
| Product Name: Human ICOS Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: ICOS;CD278;AILIM;Inducible T-cell costimulator | ||
| Target: ICOS | ||
| UNIPROT ID: Q9Y6W8 | ||
| Description: Recombinant human ICOS protein with C-terminal human Fc tag | ||
| Background: The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. | ||
| Species/Host: HEK293 | ||
| Molecular Weight: The protein has a predicted molecular mass of 39.7 kDa after removal of the signal peptide. The apparent molecular mass of ICOS-hFc is approximately 55 kDa due to glycosylation. | ||
| Molecular Characterization: ICOS(Glu21-Lys140) hFc(Glu99-Ala330) | ||
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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