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Human IFNGR1 Protein, hFc Tag

Recombinant human IFNGR1 protein with C-terminal human Fc tag


Cat.#:  11738

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11738
Product Name:   Human IFNGR1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   IFN-gamma-R1;CDw119;CD119
Target:    IFNGR1
UNIPROT ID:    P15260
Description:    Recombinant human IFNGR1 protein with C-terminal human Fc tag
Background:     This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 51.9 kDa after removal of the signal peptide. The apparent molecular mass of IFNGR1-hFc is approximately 55-100 kDa due to glycosylation.
Molecular Characterization:    IFNGR1(Glu18-Gly245) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IFNGR1 Protein, hFc Tag on SDS-PAGE under reducing condition.