$389.00
| Cat.#: 11303 |
| Product Name: Human IgG1-Fc Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: IgG1 Fc Protein |
| Target: IgG1-Fc |
| UNIPROT ID: P01857 |
| Description: Recombinant Human IgG1-Fc Protein |
| Background: IGHG1 (Immunoglobulin Heavy Constant Gamma 1 (G1m Marker)) is a Protein Coding gene. Diseases associated with IGHG1 include?Leukemia, Chronic Lymphocytic?and?Heavy Chain Deposition Disease. Among its related pathways are?Interleukin-4 and 13 signaling?and?IL4-mediated signaling events. Gene Ontology (GO) annotations related to this gene include?antigen binding. An important paralog of this gene is?IGHG3. |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 27.7 kDa after removal of the signal peptide.The apparent molecular mass of IgG1-Fc is approximately 30-40 kDa due to glycosylation. |
| Molecular Characterization: hFc(Glu99-Ala330) |
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human IgG1-Fc Protein on SDS-PAGE under reducing condition. |
