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Human IL18RA Protein, hFc Tag

Recombinant Human IL18RA Protein with C-terminal human Fc tag


Cat.#:  11753

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11753
Product Name:   Human IL18RA Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD218a;CDw218a;IL-1Rrp;IL-18R-alpha;IL-18Ralpha;IL1RRP;IL18RA;IL18Ralpha2
Target:    IL18RA
UNIPROT ID:    Q13478
Description:    Recombinant Human IL18RA Protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 61.9 kDa after removal of the signal peptide.The apparent molecular mass of IL18RA-hFc is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    IL18RA(Ala19-Arg329) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IL18RA Protein, hFc Tag on SDS-PAGE under reducing condition.