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Human IL1RA Protein, hFc Tag

Recombinant Human IL1RA Protein with C-terminal human Fc tag


Cat.#:  11656

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11656
Product Name:   Human IL1RA Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD121A;D2S1473;IL-1R-alpha;IL1R;IL1RA;P80
Target:    IL1RA
UNIPROT ID:    P14778
Description:    Recombinant Human IL1RA Protein with C-terminal human Fc tag
Background:     This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 62.3 kDa after removal of the signal peptide.The apparent molecular mass of IL1RA-hFc is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    IL1RA(Leu18-Thr332) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IL1RA Protein, hFc Tag on SDS-PAGE under reducing condition.