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Human IL2RG Protein, hFc Tag

Recombinant human IL2RG protein with C-terminal human Fc tag


Cat.#:  11744

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11744
Product Name:   Human IL2RG Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD132;CIDX;IL-2RG;IMD4;P64;SCIDX;SCIDX1
Target:    IL2RG
UNIPROT ID:    P31785
Description:    Recombinant human IL2RG protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 53.5 kDa after removal of the signal peptide. The apparent molecular mass of IL2RG-hFc is approximately 70-100 kDa due to glycosylation.
Molecular Characterization:    IL2RG(Leu23-Asn254) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human IL2RG Protein, hFc Tag on SDS-PAGE under reducing condition.