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Human LILRB5 Protein, His Tag

Recombinant Human LILRB5 Protein with C-terminal 6XHis tag


Cat.#:  11983

   Size:   100 μg

In Stock

            Product Description          
Cat.#:     11983
Product Name:   Human LILRB5 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   LIR8;CD85C;LIR-8
Target:    LILRB5
UNIPROT ID:    O75023
Description:    Recombinant Human LILRB5 Protein with C-terminal 6xHis tag
Background:     This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 48.1 kDa after removal of the signal peptide. The apparent molecular mass of LILRB5-His is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    LILRB5(Gly24-Gly458) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human LILRB5 Protein, His Tag on SDS-PAGE under reducing condition.