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Human LY6H Protein, hFc Tag

Recombinant Human LY6H Protein with C-terminal human Fc tag


Cat.#:  11908

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11908
Product Name:   Human LY6H Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   NMLY6
Target:    LY6H
UNIPROT ID:    O94772
Description:    Recombinant Human LY6H Protein with C-terminal human Fc tag
Background:     Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.[UniProtKB/Swiss-Prot Function]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of LY6H-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    LY6H(Leu26-Gly115) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human LY6H Protein, hFc Tag on SDS-PAGE under reducing condition.