Subtotal:
$445.00
$525.00
| Cat.#: 12030 | ||
| Product Name: Human/Murine/Rat BDNF Protein | ||
| Size : 10 µg, 50 µg and 100 µg | ||
| Synonyms: Brain-Derived Neurotrophic Factor;BDNF;Abrineurin | ||
| Target: BDNF | ||
| UNIPROT ID: P23560 | ||
| Description: Recombinant Human Brain-Derived Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed. | ||
| Background: Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease. | ||
| Species/Host: E.coli | ||
| Molecular Weight: 13 KDa | ||
| Molecular Characterization: Not available | ||
| Purity: Greater than 95% as determined by reducing SDS-PAGE. | ||
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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