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Human PRLR Protein, hFc Tag

Recombinant human PRLR protein with C-terminal human Fc tag


Cat.#:  11538

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11538
Product Name:   Human PRLR Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Prolactin receptor;PRL-R
Target:    PRLR
UNIPROT ID:    P16471
Description:    Recombinant human PRLR protein with C-terminal human Fc tag
Background:     This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of PRLR-hFc is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    PRLR(Gln25-Asp234) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human PRLR Protein, hFc Tag on SDS-PAGE under reducing condition.