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Human PSCA Protein, hFc Tag

Recombinant human PSCA protein with C-terminal human Fc


Cat.#:  11204

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11204
Product Name:   Human PSCA Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   PSCA;NQ206;RO232
Target:    PSCA
UNIPROT ID:    O43653
Description:    Recombinant human PSCA protein with C-terminal human Fc
Background:     This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals, this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 34.4 kDa after removal of the signal peptide.The apparent molecular mass of PSCA-hFc is approximately 40-57 kDa due to glycosylation.
Molecular Characterization:    PSCA(Leu12-Ser86) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human PSCA Protein, hFc Tag on SDS-PAGE under reducing condition.