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Human TGFA Protein, hFc Tag

Recombinant Human TGFA Protein with C-terminal human Fc tag


Cat.#:  11737

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11737
Product Name:   Human TGFA Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   TGF-alpha;ETGF;TGF type 1
Target:    TGFA
UNIPROT ID:    P01135
Description:    Recombinant Human TGFA Protein with C-terminal human Fc tag
Background:     This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 34.1 kDa after removal of the signal peptide. The apparent molecular mass of TGFA-hFc is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    TGFA(Glu24-Gln98) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human TGFA Protein, hFc Tag on SDS-PAGE under reducing condition.