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Human TGFBR1 Protein, N-hFc Tag

Recombinant human TGFBR1 Protein with N-terminal Human Fc tag
5/5

$389.00

Cat.#:  11221

   Size:   100 μg

In Stock

            Product Description          
Cat.#:     11221
Product Name:   Human TGFBR1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   AAT5;ACVRLK4;ALK-5;ALK5;ESS1;LDS1;LDS1A;LDS2A;MSSE;SKR4;tbetaR-I;TBR-i;TBRI;TGFR-1
Target:    TGFBR1
UNIPROT ID:    P36897
Description:    Recombinant human TGFBR1 Protein with N-terminal Human Fc tag
Background:     The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 36.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-TGFBR1 is approximately 40-53 kDa due to glycosylation.
Molecular Characterization:    hFc(Glu99-Ala330) TGFBR1(Leu34-Leu126)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human TGFBR1 Protein, N-hFc Tag on SDS-PAGE under reducing condition.
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