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Human TIMP4 Protein, hFc Tag

Recombinant human TIMP4 protein with C-terminal human Fc tag


Cat.#:  11553

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11553
Product Name:   Human TIMP4 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   TIMP-4
Target:    TIMP4
UNIPROT ID:    Q99727
Description:    Recombinant human TIMP4 protein with C-terminal human Fc tag
Background:     This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 48.6 kDa after removal of the signal peptide. The apparent molecular mass of TIMP4-hFc is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    TIMP4(Cys30-Pro224) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human TIMP4 Protein, hFc Tag on SDS-PAGE under reducing condition.