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Human TREM1 Protein, hFc Tag

Recombinant human TREM1 protein with C-terminal human Fc tag


Cat.#:  11583

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11583
Product Name:   Human TREM1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   TREM-1;CD354
Target:    TREM1
Description:    Recombinant human TREM1 protein with C-terminal human Fc tag
Background:     This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 46.4 kDa after removal of the signal peptide. The apparent molecular mass of TREM1-hFc is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    TREM1(Ala21-Arg200) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human TREM1 Protein, hFc Tag on SDS-PAGE under reducing condition.