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Human TweakR Protein, mFc Tag

Recombinant human TweakR protein with C-terminal mouse Fc tag
5/5

$445.00

Cat.#:  11275

   Size:   100 μg

In Stock

            Product Description          
Cat.#:     11275
Product Name:   Human TweakR Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   TNFRSF12A;GF-inducible 14;N14;weakR;D266
Target:    TweakR
UNIPROT ID:    Q9NP84
Description:    Recombinant human TweakR protein with C-terminal mouse Fc tag
Background:     TNFRSF12A (TNF Receptor Superfamily Member 12A) is a Protein Coding gene. Diseases associated with TNFRSF12A include?Multiple Sclerosis?and?Stroke, Ischemic. Among its related pathways are?ERK Signaling?and?CDK-mediated phosphorylation and removal of Cdc6
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 31.8 kDa after removal of the signal peptide.
Molecular Characterization:    TweakR(Glu28-Pro80) mFc(Pro99-Lys330)
Purity:    The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human TweakR Protein, mFc Tag on SDS-PAGE under non-reducing (NR) and reducing (R) conditions.

Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human TweakR, mFc tagged protein (11275) can bind Anti-TweakR Neutralizing antibody 28040 in a linear range of 0.64-80 ng/ml.
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