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Human YAP1 Protein, His Tag

Recombinant human YAP1 protein with C-terminal 6XHis tag


Cat.#:  11344

   Size:   100 μg

In Stock

          Product Description          
Cat.#:     11344
Product Name:   Human YAP1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   COB1;YAP;YAP2;YAP65;YKI
Target:    YAP1
UNIPROT ID:    P46937
Description:    Recombinant human YAP1 protein with C-terminal 6xHis tag
Background:     This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 55.3 kDa after removal of the signal peptide.
Molecular Characterization:    YAP1(Met1-Leu504) 6×His tag
Purity:    The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Human YAP1 Protein, His Tag on SDS-PAGE under reducing condition.