Subtotal:
$104.84
$415.00
| Cat.#: 11344 |
| Product Name: Human YAP1 Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: COB1;YAP;YAP2;YAP65;YKI |
| Target: YAP1 |
| UNIPROT ID: P46937 |
| Description: Recombinant human YAP1 protein with C-terminal 6xHis tag |
| Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 55.3 kDa after removal of the signal peptide. |
| Molecular Characterization: YAP1(Met1-Leu504) 6×His tag |
| Purity: The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human YAP1 Protein, His Tag on SDS-PAGE under reducing condition. |
