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IFNAR1 (DMC221) IgG1 Chimeric mAb

Anti-IFNAR1 (DMC221) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28170

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28170
Product Name:   Anti-IFNAR1(DMC221) IgG1 Chimeric Monoclonal Antibody
Synonyms:   Interferon alpha:beta receptor 1;IFN-R-1;IFN-alpha:beta receptor 1;CRF2-1;Type I interferon receptor 1
Description:    Anti-IFNAR1 antibody(DMC221) IgG1 Chimeric Monoclonal Antibody
Background:    The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases; which in turn phosphorylate several proteins; including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human IFNAR1
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-IFNAR1 (DMC221) on Expi293 cells transfected with human IFNAR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).