$445.00
| Cat.#: 28170 |
| Product Name: Anti-IFNAR1(DMC221) IgG1 Chimeric Monoclonal Antibody |
| Synonyms: Interferon alpha:beta receptor 1;IFN-R-1;IFN-alpha:beta receptor 1;CRF2-1;Type I interferon receptor 1 |
| Description: Anti-IFNAR1 antibody(DMC221) IgG1 Chimeric Monoclonal Antibody |
| Background: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases; which in turn phosphorylate several proteins; including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. |
| Applications: ELISA; Flow Cyt |
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 |
| Host Species: Rabbit |
| Isotype: Rabbit:Human Fc chimeric IgG1 |
| Purification: Purified from cell culture supernatant by affinity chromatography |
| Species Reactivity: Human IFNAR1 |
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
Figure 1. Flow cytometry analysis with Anti-IFNAR1 (DMC221) on Expi293 cells transfected with human IFNAR1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |
