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IGFBP7 (DMC422) IgG1 Chimeric mAb

Anti-IGFBP7 (DMC422) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28216

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28216
Product Name:   Anti-IGFBP7(DMC422) IgG1 Chimeric Monoclonal Antibody
Synonyms:   IBP-7; TAF; IGFBP-rP1; MAC25 protein
Description:    Anti-IGFBP7 antibody(DMC422) IgG1 Chimeric Monoclonal Antibody
Background:    This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity; and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity; and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene; and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human IGFBP7
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-IGFBP7 (DMC422) on Expi293 cells transfected with human IGFBP7 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).