Subtotal:
$347.00
$445.00
| Cat.#: 28216 |
| Product Name: Anti-IGFBP7(DMC422) IgG1 Chimeric Monoclonal Antibody |
| Synonyms: IBP-7; TAF; IGFBP-rP1; MAC25 protein |
| Description: Anti-IGFBP7 antibody(DMC422) IgG1 Chimeric Monoclonal Antibody |
| Background: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity; and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity; and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene; and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). |
| Applications: Flow Cyt |
| Recommended Dilutions: Flow Cyt 1:100 |
| Host Species: Rabbit |
| Isotype: Rabbit:Human Fc chimeric IgG1 |
| Purification: Purified from cell culture supernatant by affinity chromatography |
| Species Reactivity: Human IGFBP7 |
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
Figure 1. Flow cytometry analysis with Anti-IGFBP7 (DMC422) on Expi293 cells transfected with human IGFBP7 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |
